SCCS/1501/12 
                                    
                                    
                                                   
                                                   
                                                   
                                                   
                              Scientific Committee on Consumer Safety 
                                                   
                                                SCCS 
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                          THE SCCS'S NOTES OF GUIDANCE 
                                                   
                 FOR THE TESTING OF COSMETIC SUBSTANCES  
                                                   
                          AND THEIR SAFETY EVALUATION 
                                                   
                                                   
                                          8TH REVISION 
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                                                   
                        The SCCS adopted this opinion at its 17th plenary meeting 
                                         of 11 December 2012 
                
                
                       SCCS/1501/12                                                                            SCCS Notes of Guidance 
                                                                                             Nam et ipsa scientia potestas est 
                                                                                                  For knowledge itself is power 
                        
                                                                                          Francis Bacon (1561- 1626) Essays 
                        
                        
                        
                       The “Notes of Guidance for Testing of Cosmetic Ingredients and Their Safety Evaluation 
                       by the SCCS” is a document compiled by the members of the Scientific Committee on 
                       Consumer Safety (SCCS, replacing the former SCCP, SCCNFP and SCC). The document 
                       contains relevant information on the different aspects of testing and safety evaluation 
                       of  cosmetic  substances  in  Europe.  It  is  designed  to  provide  guidance  to  public 
                       authorities and cosmetic industry, in order to improve harmonised compliance with the 
                       actual cosmetic EU legislation. An important development is the 2009 legislative recast 
                       which transforms the cosmetic Directive 76/768/EEC1 into a Regulation. It must be 
                       emphasised that from 11 July 2013 onwards this Regulation (2009/1223/EC2) is fully 
                                                                                                       th                            3
                       applicable. In the meantime Directive 76/768/EEC with the 6  (Directive 93/35/EEC ) 
                              th                             4
                       and 7  (Directive 2003/15/EC ) amendments to this Directive still may be applied. 
                        
                       The "Notes of Guidance" are regularly revised and updated in order to incorporate the 
                       progress of scientific knowledge in general, and the experience gained in particular, in 
                       the field of testing and safety evaluation of cosmetic ingredients. 
                        
                       The previous revision of the Notes of Guidance took place in 2011 (SCCS/1416/11)5. 
                       Since  then,  several  new  opinions  of  importance  to  the  content  of  this  guidance 
                       document have been adopted and they form the basis of this new revision. 
                        
                       As was also the case in previous revisions, individual opinions are not provided in 
                       detail, but are briefly summarised and clearly referred to. 
                        
                       The "Notes of Guidance" should not be seen as a checklist, but have been compiled to 
                       provide  assistance  in  the  complex  process  of  the  testing  and  safety  evaluation  of 
                       cosmetic ingredients in the EU. 
                       Input of scientists from industry, other scientific committees (SCHER, SCENIHR) and 
                       Cosmetics Europe (formerly Colipa), is gratefully acknowledged. 
                        
                        
                                                                                                                  The Chairperson 
                                                                        
                       1   Council Directive 76/768/EEC of 27 July 1976 on the approximation of the laws of the Member States 
                          relating to cosmetic products. 
                          Official Journal L 262, 27/09/1976 p.169. 
                       2   Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 
                          on cosmetic products (recast). 
                          Official Journal L342, 22/12/2009 p 59. 
                       3   Council Directive 93/35/EEC of 14 June 1993 amending for the sixth time Directive 76/768/EEC on 
                          the approximation of the laws of the Member States relating to cosmetic products. 
                          Official Journal L 151, 23/06/1993 p.32. 
                       4   Directive 2003/15/EC of the European Parliament and of the Council of 27 February 2003 amending 
                          Council Directive 76/768/EEC on the approximation of the laws of the Member States relating to cosmetic 
                          products. 
                          Official Journal L66, 11/03/2003 p.26. 
                       5   SCCS/1416/11: The SCCS's Notes of Guidance for the testing of cosmetic ingredients and their safety 
                          evaluation, 7th revision, adopted by the SCCS during the 10th plenary meeting of 22 March 2011. 
                        
              SCCS Notes of Guidance                                                         SCCS/1501/12 
                                                            
                                SCIENTIFIC COMMITTEE ON CONSUMER SAFETY 
                                                            
                                                            
                                                            
                              ANGERER J.                       (DE)       
                              BERNAUER U.                      (DE)       
                              CHAMBERS C.                      (IE)       
                              CHAUDHRY M.                      (UK)       
                              DEGEN G.                         (DE)       
                              NIELSEN E.                       (DK)       
                              PLATZEK T.                       (DE)       
                              RASTOGI S.                       (DK)       
                              ROGIERS V.                       (BE)      Vice-Chair 
                              ROUSSELLE C.                     (FR)       
                              SANNER T.                        (NO)      Vice-Chair 
                              VAN BENTHEM J.                   (NL)       
                              VAN ENGELEN J.                   (NL)       
                              VINARDELL M.P.                   (ES)       
                              WARING R.                        (UK)       
                              WHITE I.                         (UK)      Chair 
                                                                          
                              Associated scientific advisors:             
                              LILIENBLUM W.                    (DE)