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Background
2000 - 2003 US FDA, Antibiotic resistance monitoring, risk assessment and
scientific support for veterinary antibiotic registration
2004 – Elanco Animal Health global microbiologist/antibiotics technical consultant
2008 – 2014 Chair of the CEESA VetPath, Pan-Eu antimicrobial resistance
monitoring program
2012 – Co-Chair of CLSI VAST sub-committee (Chair 2016 - 2020)
Editor for JAC (9 years), AAC (10 years) and IJAA (9 years +)
Over 80 peer reviewed papers and conference presentations, 2 books and 9 book
chapters
Global Surveillance Programs
Veterinary examples
FARM DANMAP
VAV SVARM
MARAN GermVet
NVAL NARMS
CIPARS JVARM
Mexican Brazil
Global Surveillance Programs
All the national programs focus predominantly on foodborne and
commensal bacteria
The data generated from these surveillance programs are used for
registration purposes, as an indicator for the emergence of resistance
and for National Risk Assessment and subsequent Risk Management
guidelines
It is therefore important to ensure that the data being generated is of
uniform quality and interpreted using a single interpretive criteria
Need for Harmonisation
Franklin et al (2001) published a guideline on the harmonisation of
surveillance programmes in animals on behalf of the Office International des
Epizooties (OIE)
a) animal species/categories (including age) to be sampled
b) for food sampling, the relative merits of sampling at the abattoir and retail outlet should be
considered. In addition to food of domestic origin, food of foreign origin may also be considered,
possibly at the port of entry of the products
c) sampling strategy to be employed, for example: active or passive collection of samples; random,
stratified or systematically collected samples; statistically based sampling or opportunistic sampling
d) samples to be collected (faeces, carcass, raw and/or processed food)
e) bacterial species to be isolated
f) antimicrobials to be used in susceptibility testing
g) standardised susceptibility testing
h) quality control – quality assurance
i) type of quantitative data to be reported
j) database design for appropriate data extraction
k) analysis and interpretation of data
l) reporting (consideration of transparency of reporting and interests of stakeholders)
Franklin A, Acar J, Anthony F, Gupta R, Nicholls T, Tamura Y, Thompson S, Threlfall EJ, Vose D, van Vuuren M, White DG, Wegener HC &
Costarrica ML (2001). Antimicrobial resistance: harmonisation of national antimicrobial resistance monitoring and surveillance programmes in
animals and in animal-derived food. Revue scientifique et technique (International Office of Epizootics) 20, 859-870
Need for Harmonisation
Veterinary Microbiology 141 (2010) 1–4
Editorial
Assessing the antimicrobial susceptibility of bacteria obtained
from animals
Stefan Schwarz, Peter Silley, Shabbir Simjee, Neil Woodford, Engeline van Duijkeren,
Alan P. Johnson and Wim Gaastra
International Journal of Antimicrobial Agents 37 (2011) 504–512
Review
Harmonisation of resistance monitoring programmes in
veterinary medicine: an urgent need in the EU?
Peter Silley, Anno de Jong, Shabbir Simjee, Valérie Thomas
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