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picture1_Nucleic Acid Hybridization Slideshare 67108 | 5 Dna Biosensors Lecture 5


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File: Nucleic Acid Hybridization Slideshare 67108 | 5 Dna Biosensors Lecture 5
dna biosensors dna biosensors principles of dna biosensors principles of dna biosensors nucleic acid hybridization perfect match stable dsdna strong hybridization one or more base mismatches weak hybridization forms of ...

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   DNA biosensors
   DNA biosensors
       Principles of DNA biosensors
       Principles of DNA biosensors
  Nucleic acid hybridization
  
      Perfect match
          stable dsDNA, strong hybridization
  
      One or more base mismatches
              weak hybridization
  Forms of DNA Biosensors
 • Electrodes
 • Chips
 • Crystals
  Types of DNA Based Biosensors
 • Optical
 • Electrochemical 
 • Piezoelectric
            Immobilization of DNA Probe 
            Immobilization of DNA Probe 
             onto Transducer Surface 
             onto Transducer Surface 
   simple adsorption 
   onto carbon surfaces 
         Immobilization of DNA Probe 
         Immobilization of DNA Probe 
          onto Transducer Surface 
          onto Transducer Surface 
  Thiolated DNA for self assembly onto gold (or platinum) transducers
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...Dna biosensors principles of nucleic acid hybridization perfect match stable dsdna strong one or more base mismatches weak forms electrodes chips crystals types based optical electrochemical piezoelectric immobilization probe onto transducer surface simple adsorption carbon surfaces thiolated for self assembly gold platinum transducers...

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