169x Filetype PPTX File size 0.91 MB Source: uoqasim.edu.iq
DNA biosensors DNA biosensors Principles of DNA biosensors Principles of DNA biosensors Nucleic acid hybridization Perfect match stable dsDNA, strong hybridization One or more base mismatches weak hybridization Forms of DNA Biosensors • Electrodes • Chips • Crystals Types of DNA Based Biosensors • Optical • Electrochemical • Piezoelectric Immobilization of DNA Probe Immobilization of DNA Probe onto Transducer Surface onto Transducer Surface simple adsorption onto carbon surfaces Immobilization of DNA Probe Immobilization of DNA Probe onto Transducer Surface onto Transducer Surface Thiolated DNA for self assembly onto gold (or platinum) transducers
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