• Man, 45 year old in 2001
  • October 2001: HCV serology 
  • January  2002: 
   –AST: 69, ALT: 121 UI/l
   –HCV RNA  
   –HCV genotype: 4c/4d
  • 15/3/02
  • Liver biopsy: 
   –2 fragments: 12 mm x 2
   –Metavir: A2 F2
  • October 2002:
   –IFN 150 µg x 3/w + RIBA 1 g/d for 1 year
  • January and September 2003: HVC RNA : 
   responder
  • 2004: HCV RNA : relapser 
  • 2004-7: 
   –No treatment for HCV
   –follow-up:
        Follow-up by non-invasive tests
                           Fibroscan   FibroMeter InflaMeter
                            M (IQR) 
                             (kPa)
               24/06/04       7.7          0.65
               18/10/05       6.3          0.69
               10/10/06       6.3          0.78        0.81
               13/11/07     6.4 (0.6)      0.65        0.67