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BRANCHES
COORDINATION CHEMISTRY
BIOINORGANIC
ORGANOMETALLIC COMPOUNDS
SYNTHETIC INORGANIC CHEMISTRY.
INORGANIC COMPOUNDS
th
Berzelius, the 19 century chemist ,
described inorganic compounds are
inanimate.
The first important synthetic inorganic
compound was ammonium nitrate for soil
fertilization.
These are synthesized for use as drugs such
as cisplatin, magnesium hydroxide etc.
Some of the compounds are used as
catalysts and reagents in organic chemistry.
Ex: lithium aluminium hydride.
Sources of inorganic compounds :
Derived from either organic or inorganic sources .
Many drugs are from plant and synthetic sources.
Definition :
Study of pharmaceutical applications of the
inorganic compounds led to the establishment of a
new avenue called pharmaceutical inorganic
chemistry.
It deals with the study of preparation, standards
of purity, limit test for determining quality ,purity
and storage conditions of all inorganic compounds.
Importance of inorganic pharmaceuticals :
Inorganic pharmaceuticals are useful in the
following ways :
Useful medicinally for their therapeutic
purpose . Ex: Astringents and antimicrobials
etc.
Pharmaceutical aids. Ex: Bentonite , talc etc.
Replenishing the normal content of body
fluids. Ex- Sodium, potassium, calcium,
chloride etc.
Used in pharmaceutical analysis . Ex –
Titrants such as potassium permanganate
etc.
Applications in pharmacy as follows :
Abrasives – Dibasic calcium phosphate .
Absorbents – Calcium carbonate .
Acidifiers – dil. Hydrochloric acid .
Adsorbents – Bismuth subnitrate .
Alkalizers - Sodium citrate .
Anaesthetics – Nitrous oxide .
Analgesic – Nitrous oxide .
Antacids – Caco3 .
Anthelmintics – Ammoniated mercury.
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