NEPHAR 407 PHARMACEUTICAL CHEMISTRY III LAB
                     MASS SPECTROMETRY 
                                    (MS)
           Assist.Prof.Dr. Banu Keşanlı
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                            Analytical Chemistry
                Instrumental Methods                         Chemical Methods
               Spectroscopy            Mass Spectrometry      ¾Titration
                                                              ¾Gravimetric Analysis
                                                              ¾Solution Chemistry
                             Optical Emission
          NMR                                  ¾FT-ICR
                         Microwave             ¾TOF
             Optical Absorption                ¾Quadrupole
                                               ¾Ion Trap
                                               ¾Linear Trap
                                               ¾Magnetic Sector
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                      Mass Spectrometry
         •  Molecular weight can be obtained from a very small sample.
         •  Mass spectrometry  (MS) is NOT a form of spectroscopy 
           because it does not involve the absorption or emission of 
           light.
         •  A beam of high-energy electrons breaks the molecule apart.
         •  The masses of the fragments and their relative abundance 
           reveal information about the structure of the molecule.
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