Clarified syllabus. Clarificaton shown in blue
 An overview of immune response : Innate and 
 adaptive immune response, primary and 
 secondary immune response, organs of 
 mammalian immune system
 Basic concept on molecular structure of 
 immunoglobulins(antibody), humoral and cellular 
 immune responses, antigen presentation, MHC
 Lymphocytes and immune response: cytotoxic T-
 cell, helper T-cell, suppressor T-cell
 Naive B-cell, plasma cell, memory B-cell
 Basic concept in Autoimmune diseases, Immunodeficiency-AIDS 
 and vaccinaton.
 Introducton to immunodiagnostcs – RIA, ELISA.
             
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      R    IA
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        Radioimmunoassay
 A radioimmunoassay (RIA) is a very sensitve in vitro assay technique 
 used to measure concentratons of substances (antgen), (for 
 example, hormone levels in blood) by use of antbodies.
 Although the RIA technique is extremely sensitve and 
 extremely specific, requiring specialized equipment, it remains among 
 the least expensive methods.
 It requires special precautons and licensing, since radioactve 
 substances are used.
    Radioimmunoassay  Method
  To perform a radioimmunoassay, a known quantty of  I 125- labeled  version of 
  the test antgen is mixed with a known amount of  cognate antbody  and 
  allowed to bind. 
  Then, a sample of serum from a patent containing an unknown quantty of that 
  same antgen is added. 
  This causes the unlabeled (or "cold") antgen from the serum to compete with 
  the radiolabeled antgen ("hot") for antbody binding sites. 
  As the concentraton of "cold" antgen is increased, more of it binds to the 
  antbody, displacing the radiolabeled variant, and reducing the rato of 
  antbody-bound radiolabeled antgen to free radiolabeled antgen. 
  The bound antgens are then separated and the radioactvity of the 
  free(unbound) antgen remaining in the supernatant is measured using 
  a gamma counter.